Systems and Synthetic Immunology
Systems and Synthetic Immunology focuses on the similarities between biology and engineering at the systems level, which are important for applying engineering theories to biology problems. With the advent of new genomic techniques, there are numerous sys
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stems and Synthetic Immunology
Systems and Synthetic Immunology
Shailza Singh Editor
Systems and Synthetic Immunology
Editor Shailza Singh National Centre for Cell Science Pune, Maharashtra, India
ISBN 978-981-15-3349-5 ISBN 978-981-15-3350-1 (eBook) https://doi.org/10.1007/978-981-15-3350-1 © Springer Nature Singapore Pte Ltd. 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Contents
1 Vaccine Design, Nanoparticle Vaccines and Biomaterial Applications���������������������������������������������������������������������������������������������� 1 Pragya Misra and Shailza Singh 2 Systems Immunology Approach in Understanding the Association of Allergy and Cancer �������������������������������������������������� 53 Sreyashi Majumdar and Sudipto Saha 3 Genome Engineering Tools in Immunotherapy������������������������������������ 73 Rashmi Dahiya, Taj Mohammad, and Md. Imtaiyaz Hassan 4 Bioinformatics Tools for Epitope Prediction ���������������������������������������� 103 Mohini Jaiswal, Shafaque Zahra, and Shailesh Kumar 5 A Chronological Journey of Breg Subsets: Implications in Health and Disease������������������������������������������������������������������������������ 125 Hamid Y. Dar, Lekha Rani, Leena Sapra, Zaffar Azam, Niti Shokeen, Asha Bhardwaj, Gyan C. Mishra, and Rupesh K. Srivastava 6 T-Cell Activation and Differentiation: Role of Signaling and Metabolic Cross-Talk ���������������������������������������������������������������������� 153 Rupa Bhowmick, Piyali Ganguli, and Ram Rup Sarkar 7 Innate Immune Signaling in Cardiac Homeostasis and Cardiac Injuries������������������������������������������������
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