The effect of chronic lymphocytic thyroiditis on patients with thyroid cancer
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WORLD JOURNAL OF SURGICAL ONCOLOGY
RESEARCH
Open Access
The effect of chronic lymphocytic thyroiditis on patients with thyroid cancer Yi Zhang*†, Xiao-peng Ma†, Fu-sheng Deng, Zheng-rong Liu, Hou-qing Wei, Xi-hong Wang and Hao Chen
Abstract Background: The purpose of this study was to investigate the association between chronic lymphocytic thyroiditis (CLT) and malignant tumors of the thyroid. Methods: A retrospective review of 647 patients who underwent thyroid surgery at the Department of Breast and Thyroid Surgery in Anhui Provincial Hospital, China in 2012 was performed. The clinicopathological characteristics of patients with thyroid malignancies and CLT were collected. CLT was diagnosed by histopathological method. Results: Among 647 patients, 144 patients had thyroid malignancies and 108 patients had been diagnosed with CLT. Moreover, in total, 44 patients had thyroid malignancies coexistent with CLT: forty-one (93.2%) patients had been diagnosed with the papillary thyroid cancer (PTC); two (4.5%) patients suffered from medullary carcinoma; and one (2.3%) patient suffered from lymphoma. The morbidity of thyroid malignancies in patients with CLT was significantly higher than that in patients without CLT (40.7% versus 18.6%; P
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