The effect of protein-enriched snacks on serum albumin concentration in non-selected haemodialysis patients
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ORIGINAL ARTICLE
The effect of protein‑enriched snacks on serum albumin concentration in non‑selected haemodialysis patients Patrik Deleaval1 · Jean Guillaume1 · Anne‑Lise Bernollin1 · Christie Lorriaux1 · Jean‑Marc Hurot1 · Brice Major1 · Manolie Mehdi1 · Charles Chazot1 Received: 1 March 2020 / Accepted: 10 October 2020 © Italian Society of Nephrology 2020
Abstract Objective Serum albumin level is not only one of the protein-energy wasting criteria but also a powerful marker of mortality in patients on haemodialysis (HD) treatment. The study aimed to assess the effect of a protein-enriched snack given during HD treatment on serum albumin level. Design and methods This prospective, single-centre, observational, non-randomized 16-month study was sub-divided into four 4-month periods. Patients on hemodialysis for more than three months and receiving a regular standard snack (8.8 g of protein) during the HD session were included and assigned during four four-month periods to receive either the standard snack or a protein-enriched snack (28.7 g). Patients were not selected based on nutritional criteria. Results Sixty-six patients completed the study. Serum albumin levels significantly increased, from 3.43 ± 0.28 g/dl in the first period (standard snack) to 3.62 ± 0.32 g/dl (p
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