Tocilizumab
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Exacerbation of skin ulcer: case report In a study of 38 patients, conducted to compare the gene-expression modification profiles among tocilizumab, tofacitinib and baricitinib for rheumatoid arthritis (RA), a patient [age and sex not stated] was described, who developed exacerbation of skin ulcer during treatment with tocilizumab [route and dosage not stated] for RA; however, the activity of RA was absolutely under control. It was determined that the exacerbation of skin ulcer occurred due to the suppression of genes involved in wound healing after tocilizumab treatment [duration of treatment to reaction onset and outcome not stated]. Koyama Y, et al. Affecting common biological processes or disparate?: Comparison of geneexpression modification profiles among targeting IL-6 and targeting specific JAK treatments. Annals of the Rheumatic Diseases 79 (Suppl.): 328-329 abstr. THU0208, Jun 2020. Available from: URL: https://ard.bmj.com/content/annrheumdis/79/ 803516262 Suppl_1/328.full.pdf [abstract]
0114-9954/20/1831-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved
Reactions 21 Nov 2020 No. 1831
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