Translational Cardiology Molecular Basis of Cardiac Metabolism, Card

Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the

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Series Editors William B. Coleman Gregory J. Tsongalis

For further volumes: http://www.springer.com/series/8176

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Cam Patterson



Monte S. Willis

Editors

Translational Cardiology Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques

Editors Cam Patterson Department of Internal Medicine Division of Cardiology McAllister Heart Institute University of North Carolina Chapel Hill North Carolina, USA

Monte S. Willis Department of Pathology & Laboratory Medicine McAllister Heart Institute University of North Carolina Chapel Hill North Carolina, USA

ISBN 978-1-61779-890-0 ISBN 978-1-61779-891-7 (eBook) DOI 10.1007/978-1-61779-891-7 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2012939492 © Springer Science+Business Media, LLC 2012 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Humana Press is a brand of Springer Springer is part of Springer Science+Business Media (www.springer.com)

We dedicate this book to our families, Tina, Connor, and Declan Willis and Kris, Celia, Anna Alyse, and Graham Patterson, who gave us the support and inspiration we needed to complete this task.

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Preface

The primary goal of this textbook is to provide an overview of cutting-edge and emerging topics in cardiology as seen by experts from