Using electronic AKI alerts to define the epidemiology of acute kidney injury in renal transplants
- PDF / 803,397 Bytes
- 10 Pages / 595.276 x 790.866 pts Page_size
- 39 Downloads / 171 Views
ORIGINAL ARTICLE
Using electronic AKI alerts to define the epidemiology of acute kidney injury in renal transplants Aled Jones1 · Jennifer Holmes2 · Michael Stephens1 · John Geen3 · John Williams4 · Kieron Donovan2 · Aled O. Phillips4 Received: 6 March 2020 / Accepted: 16 September 2020 © The Author(s) 2020
Abstract Background Little is known regarding the impact of acute kidney injury (AKI) on renal transplant outcome. Our aim was to define the incidence and outcome of AKI in renal transplant patients using data collected from a national AKI electronic alert system Methods The study represents a prospective national cohort study collecting data on 1224 renal transplants recipients with a functioning renal transplant, between April 2015 and March 2019. Results Four hundred forty patients experienced at least one episode of AKI giving an incidence rate of 35.4%. Sixty-four point seven% of episodes were AKI stage 1, 7.3% AKI stage 2 and 28% AKI stage 3. Only 6.2% of episodes occurred in the context of rejection. Forty-three point five% of AKI episodes were associated with sepsis. AKI was associated with preexisting renal dysfunction, and a primary renal diagnosis of diabetic nephropathy. AKI was more prevalent in recipients from a donor after cardiac death (26.4% vs. 21.4%, p
Data Loading...
