Varicella zoster virus vaccine
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Disseminated varicella zoster infection: case report A 33-year-old woman developed disseminated varicella zoster infection following treatment with varicella zoster virus vaccine. The woman had a history of recurrent mild upper respiratory infections and splenomegaly (noted at the age of 5). She developed a disseminated vesicular rash on extremities and trunk with 40–50 non-synchronously evolving lesions 2 weeks after receiving varicella zoster virus vaccine [route and dosage not stated; post-partum attenuated varicella vaccine]. On physical examination, she showed splenomegaly and considered as a sequela of infectious mononucleosis. A concern for varicella zoster virus vaccine strain disseminated infection was made. On further examinations, underlying diagnosis of paradoxical CD4 lymphopenia and autoimmune lymphoproliferative syndrome were considered. The woman’s lesions eventually crusted and recovered within 10 days from it’s onset without further clinical complications. Lisco A, et al. Paradoxical CD4 Lymphopenia in Autoimmune Lymphoproliferative Syndrome (ALPS). Frontiers in Immunology 10: 2019. Available from: URL: http:// 803496976 doi.org/10.3389/fimmu.2019.01193
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Reactions 22 Aug 2020 No. 1818
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