Verruca Vulgaris
Human Papilloma Virus (HPV) infection may lead to the formation of common warts (verruca vulgaris)
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Verruca Vulgaris
Human Papilloma Virus (HPV) infection may lead to the formation of common warts (verruca vulgaris) Histologic Features: • Marked papillarity: acanthosis and elongation of rete ridges • Intoeing of rete ridges at edges
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Columns of parakeratosis at rete peaks Hypergranulosis at valleys between rete ridges Dermal papillae with dilated, ectatic capillaries Viral cytopathic changes with keratohyaline granule clumping (“koilocytes”) in upper epidermis
K.S. Masterpol et al., Atlas of Essential Dermatopathology, DOI 10.1007/978-1-4471-4471-7_5, © Springer-Verlag London 2013
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Verruca Vulgaris
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Tiers of Parakeratosis
Dilated Capillaries
Epidermis
Dermis Valleys of Hypergranulosis Fig. 5.1 Sketch of verruca vulgaris. The hyperkeratotic keratin forms tiers of parakeratosis alternating with valleys of keratinocytic hypergranulosis. Dilated capillaries are present in papillary dermis
Fig. 5.2 Verruca vulgaris. A parakeratotic tier is present at the left of the image with underlying hypogranulosis. Hemorrhage is observed in the superficial stratum corneum and prominence of the granular cell layer is present in the valleys between the rete ridges
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