Vertebrate Embryogenesis Embryological, Cellular, and Genetic Method
One of the striking findings of modern developmental biology has been the high degree of conservation of signaling and developmental mechanisms amongst different animal species. Such conservation allows information learned from a given organism to be
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MO L E C U L A R BI O L O G Y
Series Editor John M. Walker School of Life Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For other titles published in this series, go to www.springer.com/series/7651
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Vertebrate Embryogenesis Embryological, Cellular, and Genetic Methods
Edited by
Francisco J. Pelegri Department of Genetics, University of Wisconsin, Madison, WI, USA
Editor Francisco J. Pelegri Department of Genetics University of Wisconsin Madison, WI, USA [email protected]
ISSN 1064-3745 e-ISSN 1940-6029 ISBN 978-1-61779-209-0 e-ISBN 978-1-61779-210-6 DOI 10.1007/978-1-61779-210-6 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011933224 © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Printed on acid-free paper Humana Press is part of Springer Science+Business Media (www.springer.com)
Preface One of the striking findings of modern developmental biology has been the high degree of conservation of signaling and developmental mechanisms among different animal species. Such conservation allows information learned from a given organism to be applicable to other species, including humans, and has validated the use of a few model systems to deduce general biological principles. In spite of this underlying conservation, however, each species has unique characteristics arising from its evolutionary history. The picture emerging from the ongoing research on a limited number of model organisms is thus a patchwork of knowledge that reflects those unique systems. The important contribution of other less-studied, emerging model systems will be invaluable to fill these gaps. The modern developmental biologist strives to fill this currently fragmented picture in search of a more refined, fuller view, which better reflects both the underlying biological principles and the genetic continuum between species. While studying the same process in various types of organisms may highlight common developmental mechanisms, individual features of species differ, each providing advantages for analyzing various aspects of a given process. With regard to laboratory research, some approaches may be more feasible in some species than in others; for example, the ease of embryological manipulations in amphibians and chicken set them apart as
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