X-ray Free Electron Lasers A Revolution in Structural Biology
The timely volume describes recent discoveries and method developments that have revolutionized Structural Biology with the advent of X-ray Free Electron Lasers. It provides, for the first time, a comprehensive examination of this cutting-edge technology.
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ray Free Electron Lasers A Revolution in Structural Biology
X-ray Free Electron Lasers
Sébastien Boutet • Petra Fromme Mark S. Hunter Editors
X-ray Free Electron Lasers A Revolution in Structural Biology
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Editors Sébastien Boutet SLAC National Accelerator Laboratory Menlo Park, CA, USA
Petra Fromme School of Molecular Sciences Arizona State University Tempe, AZ, USA
Mark S. Hunter SLAC National Accelerator Laboratory Menlo Park, CA, USA
ISBN 978-3-030-00550-4 ISBN 978-3-030-00551-1 (eBook) https://doi.org/10.1007/978-3-030-00551-1 Library of Congress Control Number: 2018962550 © Springer Nature Switzerland AG 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
“I was captured for life by chemistry and by crystals.” Dorothy Crowfoot Hodgkin “The limits of the possible can only be defined by going beyond them into the impossible.” Arthur C. Clarke “I was taught that the way of progress is neither swift nor easy.” Marie Curie “It’s kind of fun to do the impossible.” Walt Disney
X-ray free electron lasers (FELs) are revolutionary tools in the world of X-ray science. The new capabilities that they have already provided, and potentially can enable, have led to a growing revolution in structural biology. Biology using X-ray FELs is a nascent field, with the very first results of X-ray diffraction from protein crystals using an X-ray FEL published in 2011. This book represents the first collection of contributions from scientists in the field who are specifically devoted to this topic, focusing on the most emerging techniques as well as current and future challenges. It is our sincere hope that all readers enjoy reading about the revolutionary techniques developed, the obstacle
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