Yeast Single Cell Oils from Bioresources: Current Developments in Production and Applications
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BIOCONVERSION (SK BRAR AND G KAUR, SECTION EDITORS)
Yeast Single Cell Oils from Bioresources: Current Developments in Production and Applications Sheetal Bandhu 1
&
Anita Srivastava 2 & Debashish Ghosh 3 & Tapan Kumar Chaudhuri 1
Accepted: 29 September 2020 # Springer Nature Switzerland AG 2020
Abstract Purpose of Review The purpose of this review is to describe the process of conversion of bioresources into lipids by yeasts and their applications. Current challenges at industrial scale and scope for future developments have been discussed. Recent Findings Sustainable routes for industrial yeast lipid production using innovative techniques for pretreatment to downstream processing are the targets for research. The latest blossoming research areas are genetic modification strategies to improve lipid production and recovery along with the production of non-native lipid–derived products. Summary Yeast lipid has emerged as a bio-similar to vegetable oils that can be used for the production of fuel, chemicals, polymers, and nutraceuticals. The main stages with high-cost contribution in bioconversion of biomass to lipid are identified. For an economically feasible product, the lipid yields must be improved and a combination of high-value and low-value products should be produced. Keywords Bioconversion . Bioresources . Lignocellulosic biomass . Yeast . Single cell oil . Microbial lipid
Introduction Fossil fuels are a source of an array of products ranging from fuel, kerosene, chemicals, and polymers. Rising concerns on their unsustainability led to the development of bio-based products derived from plant oils as alternate feedstock for biofuel and oleochemicals. However, their primary use as food, the associated change in land use, and deforestation limit their extended use [1]. In this scenario, microbial oils emerged as biosimilars of plant oils. Microbial oils also called “single cell oils” are lipid molecules synthesized and accumulated intracellularly in few microbes. The majority of this lipid is in the triacylglycerol form having approximately the same This article is part of the Topical Collection on Bioconversion * Sheetal Bandhu [email protected] 1
Kusuma School of Biological Sciences, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India
2
Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India
3
Biochemistry and Biotechnology Area, Material Resource Efficiency Division, CSIR-Indian Institute of Petroleum, Dehradun 248 005, India
fatty acid distribution as vegetable oils. The non-competition with food production, low land and water requirement, production independent of regional and seasonal variations, fast process cycles, and higher scalability have increased the importance of microbial oils over vegetable oils for the fuel and chemical industry [2–4]. Lipids form the structural components and act as energy storage molecules in all microbes, but only few can make oil in sufficient quantities for in
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