Agreement in central corneal thickness measurement between Corvis ST and ocular response analyzer
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ORIGINAL PAPER
Agreement in central corneal thickness measurement between Corvis ST and ocular response analyzer Ramin Salouti . Reza Razeghinejad . Nasrin Masihpour . Maryam Ghoreyshi . M. Hossein Nowroozzadeh
Received: 9 September 2019 / Accepted: 18 May 2020 Ó Springer Nature B.V. 2020
Abstract Purpose To evaluate the agreement and interchangeability of noncontact devices of ocular response analyzer (ORA) and the Corvis ST in central corneal thickness measurement. Methods In this prospective comparative study, central corneal thickness (CCT) readings of 284 healthy, nonglaucoma subjects, without previous ocular surgery, were measured with ORA and Corvis ST. Only data from right eyes were analyzed. The mean values of CCT measurements by the ORA versus Corvis ST were compared with the paired sample t test. Bland–Altman plots and 95% limits of agreement (95% LOA) were used to assess the agreement between the measurements of the two devices.
Results The mean (± standard deviation) age of the participants was 28.0 ± 4.9 years, and 36.6% were male. The mean CCT measurements were 555 ± 32 lm by the ORA and 536 ± 32 lm with the Corvis ST (P \ 0.001). The Pearson correlation coefficient was 0.964 (P \ 0.001). The 95% LOA between the ORA and the Corvis ST was 2.2 to 35.9 lm. Conclusions The ORA measured the CCT up to 35.9 lm greater than Corvis ST. Therefore, the two devices may not be used interchangeably for measuring CCT. Keywords Agreement Central corneal thickness Corvis ST Ocular response analyzer
Introduction R. Salouti N. Masihpour M. H. Nowroozzadeh (&) Poostchi Ophthalmology Research Center, Poostchi Clinic, Shiraz University of Medical Sciences, Zand Street, 7134997446 Shiraz, Iran e-mail: [email protected] R. Salouti M. Ghoreyshi Salouti Cornea Research Center, Salouti Eye Clinic, Shiraz, Iran R. Razeghinejad Glaucoma Service, Wills Eye Hospital, Philadelphia, PA, USA M. Ghoreyshi Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
The measurement of central corneal thickness (CCT) is required for diagnosis of corneal ectasias and Fuchs’ endothelial dystrophy [1], preoperative evaluation of refractive surgery [2], and assessment of the corneal endothelial function in a contact lens wearer [3]. It is particularly important for exact measurement of intraocular pressure (IOP) in glaucoma and ocular hypertension [4, 5]. A meta-analysis by Doughty and Zaman [6] showed that a 10% difference in CCT would result in a 3.4-mmHg difference in IOP. In the Ocular Hypertension Treatment Study, each 40-lm reduction in CCT was associated with a relative risk of 1.71 (95% confidence interval, 1.40–2.09) for
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development of primary open-angle glaucoma [4]. It is recommended that not only the IOP readings, but also CCT is to be recorded for a glaucoma workup to define a target IOP [7, 8]. In refractive surgery, overestimation or underestimation of corneal thickness in patients undergoing corneal ablative p
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