Antimicrobial Peptides Methods and Protocols
This volume provides basic and advanced laboratory protocols for the non-specialist and the experienced researcher. Chapters are divided into three parts covering synthesis and characterization of AMPs, studying the interaction of AMPs with model systems
- PDF / 21,872,678 Bytes
- 430 Pages / 504.63 x 737.01 pts Page_size
- 90 Downloads / 203 Views
Paul R. Hansen Editor
Antimicrobial Peptides Methods and Protocols
Methods
in
Molecular Biology
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Antimicrobial Peptides Methods and Protocols
Edited by
Paul R. Hansen Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Editor Paul R. Hansen Department of Drug Design and Pharmacology Faculty of Health and Medical Sciences University of Copenhagen Copenhagen, Denmark
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-6735-3 ISBN 978-1-4939-6737-7 (eBook) DOI 10.1007/978-1-4939-6737-7 Library of Congress Control Number: 2016955825 © Springer Science+Business Media LLC 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Humana Press imprint is published by Springer Nature The registered company is Springer Science+Business Media LLC The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.
Preface Antibiotics have saved millions of lives and helped shape modern medicine. However, the emergence of multidrug-resistant pathogens has become a global health problem, and novel approaches to antimicrobial therapy are urgently needed. Since their discovery in the early 1980s, antimicrobial peptides (AMPs) have attracted considerable interest as novel antibiotics. AMPs are produced by most living organisms and constitute the first line of defense against invading pathogens. AMPs display broad-spectrum antimicrobial activity, paired with rapid and selective bactericidal activity. Furthermore, they can display anti-biofilm, anticancer, anti-virulence, lipopolysaccharide-neutralizing, and immunomodulatory activities. The aim of this volume of Methods in Molecular Biology: Antimicrobial Peptides is to provide basic a
