Aptamers in Biotechnology

This book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid recep

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tharina Urmann Johanna-Gabriela Walter   Editors

Aptamers in Biotechnology

174 Advances in Biochemical Engineering/Biotechnology Series Editor T. Scheper, Hannover, Germany Editorial Board S. Belkin, Jerusalem, Israel T. Bley, Dresden, Germany J. Bohlmann, Vancouver, Canada M.B. Gu, Seoul, Korea (Republic of) W.-S. Hu, Minneapolis, USA B. Mattiasson, Lund, Sweden H. Seitz, Potsdam, Germany R. Ulber, Kaiserslautern, Germany A.-P. Zeng, Hamburg, Germany J.-J. Zhong, Shanghai, China W. Zhou, Shanghai, China

Aims and Scope This book series reviews current trends in modern biotechnology and biochemical engineering. Its aim is to cover all aspects of these interdisciplinary disciplines, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, molecular biology, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the field over the past 3–5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, volumes are edited by well-known guest editors. The series editor and publisher will, however, always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English. In references, Advances in Biochemical Engineering/Biotechnology is abbreviated as Adv. Biochem. Engin./Biotechnol. and cited as a journal.

More information about this series at http://www.springer.com/series/10

Katharina Urmann • Johanna-Gabriela Walter Editors

Aptamers in Biotechnology With contributions by J. Bahnemann  N. Bahner  E. Boschetti  J. G. Bruno  V. Calzada  B. Chaterjee  A. Eilers  H. Kaur  G. Perret  M. Plach  J.-A. Preuß  P. Reich  T. Schubert  T. K. Sharma  J. Walter  S. Witt

Editors Katharina Urmann Basel, Switzerland

Johanna-Gabriela Walter University Hannover Gottfried-Wilhelm Leibniz Hannover, Niedersachsen, Germany

ISSN 0724-6145 ISSN 1616-8542 (electronic) Advances in Biochemical Engineering/Biotechnology ISBN 978-3-030-54060-9 ISBN 978-3-030-54061-6 (eBook) https://doi.org/10.1007/978-3-030-54061-6 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and