Aspirin
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Mediastinal haematoma: case report A 59-year-old man developed a mediastinal haematoma while receiving aspirin for brain infarction. The man had undergone haemodialysis for 16 years for chronic renal failure and had received aspirin 100 mg/day for 4 years. He reported a dull pain in the upper right area of his back and a dry cough that had been increasing for 3 weeks. A chest x-ray revealed a widening of his upper mediastinal shadow, which had not been present on an x-ray taken 2 days previously. A CT scan showed a large mass in his upper mediastinum. Because of the mass, his superior vena cava was narrowed and crescent-shaped. The mass was located among his trachea, superior vena cava and ascending aorta. The man was hospitalised. After 2 weeks, an MRI scan showed that the mass had reduced in size. The T1-weighted image revealed left thorax pleural effusion. His symptoms gradually disappeared. His clinical and imaging results were consistent with non-traumatic mediastinal haemorrhage. Subsequently, follow-up T1-weighted images showed that the mass had gradually become smaller. After 1 year, the mass and pleural effusion had disappeared. Author comment: "The predisposition for our patient may have been the combination of renal failure, hemodialysis, and aspirin therapy." Kamiyoshihara M, et al. Spontaneous mediastinal hematoma presenting as a mass. 801090594 Journal of Thoracic Oncology 2: 544-545, No. 6, Jun 2007 - Japan
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Reactions 28 Jul 2007 No. 1162
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