Associations between pre-pregnancy body mass index and gestational weight gain with pregnancy outcomes in women with pol
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Diabetology & Metabolic Syndrome Open Access
RESEARCH
Associations between pre‑pregnancy body mass index and gestational weight gain with pregnancy outcomes in women with polycystic ovary syndrome Lirui Zhang, Wei Zheng, Cheng Liu, Xin Liang, Li Zhang, Zhihong Tian and Guanghui Li*
Abstract Background: The influence of pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) on perinatal outcomes of women with polycystic ovary syndrome (PCOS) remains unclear. Therefore, we explored how the above indicators influence pregnancy outcomes in women with PCOS. Methods: A retrospective study was conducted involving the baseline characteristics, laboratory data, and pregnancy outcomes of 722 pregnant women with PCOS. Subjects were grouped in a way to find out risks in their pregnancy outcomes. Multivariable logistic regression analysis was performed to investigate how BMI and GWG were associated with perinatal outcomes. Results: Among women with PCOS, underweight increased the risk of small for gestational age (SGA) (OR 12.35, 95% CI 3.56–42.82), but reduced the risk of large for gestational age (LGA). Overweight but not obese women were more susceptible to developing preeclampsia (PE) than women with normal weight. In PCOS women with BMI
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