Auxiliary role of mesenchymal stem cells as regenerative medicine soldiers to attenuate inflammatory processes of severe
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FULL LENGTH REVIEW
Auxiliary role of mesenchymal stem cells as regenerative medicine soldiers to attenuate inflammatory processes of severe acute respiratory infections caused by COVID-19 Peyvand Parhizkar Roudsari . Sepideh Alavi-Moghadam . Moloud Payab Forough Azam Sayahpour . Hamid Reza Aghayan . Parisa Goodarzi . Fereshteh Mohamadi-jahani . Bagher Larijani . Babak Arjmand
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Received: 17 April 2020 / Accepted: 13 June 2020 Ó Springer Nature B.V. 2020
Abstract Acute respiratory infections as one of the most common problems of healthcare systems also can be considered as an important reason for worldwide morbidity and mortality from infectious diseases. Coronaviruses are a group of well-known respiratory viruses that can cause acute respiratory infections. At the current state, the 2019 novel coronavirus is cited as the most worldwide problematic agent for the respiratory system. According to investigations, people P. Parhizkar Roudsari B. Arjmand (&) Metabolomics and Genomics Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran e-mail: [email protected] P. Parhizkar Roudsari e-mail: [email protected] S. Alavi-Moghadam H. R. Aghayan B. Arjmand Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism MolecularCellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran e-mail: [email protected] H. R. Aghayan e-mail: [email protected] M. Payab Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran e-mail: [email protected]
with old age and underlying diseases are at higher risk of 2019 novel coronavirus infection. Indeed, they may show a severe form of the disease (with severe acute respiratory infections). Based on the promising role of cell therapy and regenerative medicine approaches in the treatment of several life-threatening diseases, it seems that applying cell-based approaches can also be a hopeful strategy for improving subjects with severe acute respiratory infections caused by the 2019 novel F. A. Sayahpour Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran e-mail: [email protected] P. Goodarzi F. Mohamadi-jahani Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran e-mail: [email protected] F. Mohamadi-jahani e-mail: [email protected] B. Larijani Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran e-mail: [email protected]
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coronavirus. Herein, due to the amazing effects of mesenchymal stem cells in the treatment of various diseases, this review focuses on the auxiliary role
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