Azathioprine
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Sweet’s syndrome in an elderly patient: case report A 75-year-old man developed Sweet’s syndrome during treatment with azathioprine [therapeutic indication not stated]. The man, whose medical history was significant for Crohn’s disease, was hospitalised on the suspicion of sepsis. Examination at that time showed fever and a maculopapular skin eruption involving his extremities. Over the next 2 days, his eruption became painful and pustular and progressed to include his trunk, palms and soles. A drug-related eruption was suspected and a review of his medications showed that he had started taking azathioprine [dosage and route not stated] 2 weeks before hospitalisation. He was thought to have an azathioprine-induced reaction and a skin biopsy showed results consistent with acute febrile dermatosis: Sweet’s syndrome. Azathioprine was withdrawn with subsequent prompt resolution. Author comment: "Azathioprine-induced Sweet’s syndrome . . . [is a] rare adverse [effect]". Grelle JL, et al. Azathioprine-induced acute febrile neutrophilic dermatosis (Sweet’s syndrome). BMJ Case Reports : No. 200405, 16 Aug 2013. Available 803095396 from: URL: http://dx.doi.org/10.1136/bcr-2013-200405 - USA
0114-9954/13/1477-0001/$14.95 Adis © 2013 Springer International Publishing AG. All rights reserved
Reactions 9 Nov 2013 No. 1477
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