Impact of gastric Helicobacter pylori infection on nasal mucociliary clearance

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RHINOLOGY

Impact of gastric Helicobacter pylori infection on nasal mucociliary clearance Ender Şahin1   · Mehmet Kağan Katar2   · Ilknur Haberal Can1  Received: 3 April 2020 / Accepted: 26 May 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Objectives  This study aimed to investigate the relationship between the presence of gastric Helicobacter pylori (HP) infection and nasal mucociliary clearance (NMC) time and to analyze the effect of HP eradication on NMC time. Materials and methods  Patients who underwent gastric biopsy and had a positive result for HP constituted the study group, while the control group consisted of the patients who had a negative biopsy result. Two groups were compared in terms of NMC times. Quadruple medication therapy was given to HP-positive patients for 14 days for eradication and NMC time was measured again in these patients 8 weeks after eradication. Statistical analyses were performed with SPSS software (version 22.0; SPSS, Chicago, Illinois, USA). Results  There were 60 patients in the study group (HP +), while the control group (HP −) included 50 patients. Mean NMC times were 12.86 ± 2.62 and 8.32 ± 2.24 for the study and control groups, respectively (p