Bioactive Compounds from Marine Extremophiles
This SpringerBrief sheds new light on bioactive materials from marine extremophiles. It deals with all aspects of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or lead to novel drugs for hum
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Lesley-Ann Giddings David J. Newman
Bioactive Compounds from Marine Extremophiles
SpringerBriefs in Microbiology Extremophilic Bacteria
Series editors Sonia M. Tiquia-Arashiro, Dearborn, MI, USA Melanie Mormile, Rolla, MO, USA
More information about this series at http://www.springer.com/series/11917
Lesley-Ann Giddings David J. Newman •
Bioactive Compounds from Marine Extremophiles
123
Lesley-Ann Giddings Natural Products Branch, Developmental Therapeutics Program NCI Frederick, MD USA
ISSN 2191-5385 SpringerBriefs in Microbiology ISBN 978-3-319-14360-6 DOI 10.1007/978-3-319-14361-3
David J. Newman Natural Products Branch, Developmental Therapeutics Program NCI Frederick, MD USA
ISSN 2191-5393 (electronic) ISBN 978-3-319-14361-3
(eBook)
Library of Congress Control Number: 2014958284 Springer Cham Heidelberg New York Dordrecht London © The Author(s) 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)
Contents
Bioactive Compounds from Marine Extremophiles . . . . . . . . . 1 Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Culturable Marine Microbes . . . . . . . . . . . . . . . . . . . . . . . . 2.1 Novel Cytotoxic Agents . . . . . . . . . . . . . . . . . . . . . . . 2.2 Antioxidants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2.3 Anti-infective Agents . . . . . . . . . . . . . . . . . . . . . . . . . 2.4 Selective Enzyme Inhibitors . . . . . . . . . . . . . . . . . . . . 2.5 Anti-inflammatory Agents . . . . . . . . . . . . . . . . . . . . . . 2.6 Agents that Prevent Cardiovascular Disease. . . . . . . . . . 3 Culturable Microorganisms: Piezophiles and Deep-Sea Environments. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3.1 Anti-infective Agents . . . . . . . . . . . . . . . . . . . . . . . . . 3.2 Cytotoxic Agents . . . . . . . . . . . . . .
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