Cancer history and other personal factors affect quality of life in patients with hepatitis C
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Cancer history and other personal factors affect quality of life in patients with hepatitis C Sara H Olson*1, Sandy Iyer6, Jennifer Scott1, Orry Erez1, Shelby Samuel2, Temima Markovits2, Myron Schwartz3, Charlene Toro3, Maya GambarinGelwan4 and Robert C Kurtz5 Address: 1Unversity of Michigan Medical School, 1301 Catherine Road, Ann Arbor, MI 48109, USA, 2Department of Medicine, North General Hospital, 50 East 118th St., New York, NY 10035, USA, 3Department of Surgery, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, 1190 5th Ave., New York, NY 10029, USA, 4Department of Medicine, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, 1190 5th Ave., New York, NY 10029, USA, 5Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Ave., New York, NY 10021, USA and 6Bronx Veteran Affairs Medical Center, Bronx, NY 10468, USA Email: Sara H Olson* - [email protected]; Sandy Iyer - [email protected]; Jennifer Scott - [email protected]; Orry Erez - [email protected]; Shelby Samuel - [email protected]; Temima Markovits - [email protected]; Myron Schwartz - [email protected]; Charlene Toro - [email protected]; Maya GambarinGelwan - [email protected]; Robert C Kurtz - [email protected] * Corresponding author
Published: 16 June 2005 Health and Quality of Life Outcomes 2005, 3:39 39
doi:10.1186/1477-7525-3-
Received: 14 April 2005 Accepted: 16 June 2005
This article is available from: http://www.hqlo.com/content/3/1/39 © 2005 Olson et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: Although patients with chronic hepatitis C (CHC) have been found to have reduced quality of life, little is known about how other characteristics affect their quality of life. The purpose of this study was to investigate the effect of other characteristics, including history of cancer, on quality of life in patients with CHC. Methods: One hundred forty patients from clinics at three hospitals in New York City completed a detailed epidemiologic interview about demographic and lifestyle characteristics and the SF-36 measuring health-related quality of life. We compared results from our patients to normative data using t-tests of differences between means. We used multivariate analyses to determine other personal and health-related factors associated with quality of life outcomes. Results: Compared to normative data, these patients had reduced quality of life, particularly on physical functioning. The summary Physical Component Score (PCS) was 45.4 ± 10.6 and the Mental Component Score (MCS) was 48.2 ± 11.1, vs norms of 50 ± 10.0; p-values were 2 drinks of beer, wine, or liquor per day, on average, for men, and >1 drink per day for women. d patients
below the norms for women on bo
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