Cardiac Sarcoidosis Key Concepts in Pathogenesis, Disease Management

Sarcoidosis remains an elusive diagnosis despite advanced technology available to clinicians in most major hospitals. Once diagnosed, the disease can be progressive and disabling or remain quiescent for years. It can affect any organ, but of course, one o

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Cardiac Sarcoidosis

Key Concepts in Pathogenesis, Disease Management, and Interesting Cases

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Cardiac Sarcoidosis

Andrew M. Freeman • Howard D. Weinberger Editors

Cardiac Sarcoidosis Key Concepts in Pathogenesis, Disease Management, and Interesting Cases

Editors Andrew M. Freeman Department of Medicine Division of Cardiology National Jewish Health Denver, CO USA

Howard D. Weinberger Department of Medicine Division of Cardiology National Jewish Health Denver, CO USA

ISBN 978-3-319-14623-2 ISBN 978-3-319-14624-9 DOI 10.1007/978-3-319-14624-9

(eBook)

Library of Congress Control Number: 2015934579 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface

Sarcoidosis remains an elusive diagnosis even in this day and age with fantastic technology available in nearly any sizeable city. Further, once diagnosed, the disease can be progressive and disabling or remain quiescent for years. It can affect any organ, but of course, one of the greatest concerns is cardiac involvement which can lead to sudden death, arrhythmia, and heart failure, in addition to a great many other complications. This handbook is meant to serve as a clinician’s field guide to diagnosing, managing, and treating cardiac sarcoidosis. Much of the epidemiology, pathophysiology, and treatments are reviewed with a strong clinical angle to all discussions in an effort to provide high yield and immediately implementable concepts at the bedside. You will find clear commentary on virtually any situation to be encountered in this disease process and clear direction on how to proceed in diagnosing and managing the disease. The major caveat is that there is still no gold standard in diagnosing the disease, and even worse, no strong consensus on treatment options. Despite this, our authors have worked hard to p