Cell Biology and Pathology of Myelin Evolving Biological Concepts an
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ALTSCHUL SYMPOSIA SERIES Series Editors: Sergey Fedoroff and Gary D. Burkholder Volume I • ATHEROSCLEROSIS: Cellular and Molecular Interactions in the Artery Wall Edited by Avrum 1. Gottlieb, B. Lowell Langille, and Sergey Fedoroff Volume 2 • BIOLOGY AND PATHOLOGY OF ASTROCYTE-NEURON INTERACTIONS Edited by Sergey Fedoroff, Bernhard H. 1. Juurlink, and 1. Ronald Doucette Volume 3 • NEURAL CELL SPECIFICATION: Molecular Mechanisms and Neurotherapeutic Implications Edited by Bernhard H. J. Juurlink, Patrick H. Krone, William M. Kulyk, Valerie M. K. Verge, and 1. Ronald Doucette Volume 4 • CELL BIOLOGY AND PATHOLOGY OF MYELIN: Evolving Biological Concepts and Therapeutic Approaches Edited by Bernhard H. 1. Juurlink, Richard M. Devon, 1. Ronald Doucette, Adil J. Nazarali. David J. Schreyer, and Valerie M. K. Verge
CELL BIOLOGY AND PATHOLOGY OF MYELIN Evolving Biological Concepts and Therapeutic Approaches Edited by
Bemhard H. 1. Juurlink Richard M. Devon J. Ronald Doucette Adil 1. N azarali David 1. Schreyer and
Valerie M. K. Verge University of Saskatchewan Saskatoon, Saskatchewan, Canada
SPRINGER SCIENCE+BUSINESS MEDIA, LLC
Llbrary of Congress Cataloglng-ln-Publlcatlon Data
Cell biology and pathology of myelln evolving biological concepts and therapeutic approaches I edited by Bernhard H.J. Juurlink •. ,. let a1.l. p. cm. -- (Alschul symposia ser ies ; v. 4) Includes bibllographical references and index. 1. Myelin sheath--Pathophysiology--Congresses. 2. Demyelination-Congresses. 3. Myellnation--Congresses. 4. Myelin protelns-Congresses. I. Juurlink. B.H.J .• 1946II. Series. RC366.C45 1997 97-8136 616.8·047--dc21 CIP
ISBN 978-1-4613-7726-9
ISBN 978-1-4615-5949-8 (eBook)
DOI 10.1007/978-1-4615-5949-8 Proceedings of the Fourth International Altschul Symposium on Cel! Biology and Pathology of Myelin: Evolving Biological Concepts and Therapeutic Approaches, held June 27-29, 1996, in Saskatoon, Saskatchewan, Canada
© 1997 Springer Science+Business Media New York Originally published by Plenum Press New York in 1997 http://www.plenum.com 10987654321 AII rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher
PREFACE
This volume contains papers presented at the Fourth International Altschul Symposium, held June 27-29, 1996, at the University of Saskatchewan in Saskatoon, Saskatchewan, Canada. The Altschul Symposia Series are held in memory of Rudolf Altschul, a graduate of the University of Prague and a pioneer in the fields of vascular and nervous system biology. Dr. Altschul was head of the Department of Anatomy at the University of Saskatchewan from 1955 to 1963. The Altschul Symposia are made possible by an endowment left by Anni Altschul, Dr. Altschul's wife, and by other contributions given by the sponsors listed at the end of this Preface. The objective of the Fourth Altschul Symposium, entitled Cell Biologv an
