Cell Biology of the Ovary Stem Cells, Development, Cancer, and Clini
This unique compilation focuses on a very curious organ, the ovary. There are still many unknown facts about the origins of ovarian tissue and ovarian cancer, and each chapter describes in detail the latest insights into the ovary from basic to clinical a
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Cell Biology of the Ovary
Hidetaka Katabuchi ∙ Takashi Ohba Takeshi Motohara Editors
Cell Biology of the Ovary Stem Cells, Development, Cancer, and Clinical Aspects
Editors Hidetaka Katabuchi Department of Obstetrics and Gynecology Faculty of Life Sciences Kumamoto University Kumamoto Japan
Takashi Ohba Department of Obstetrics and Gynecology Faculty of Life Sciences Kumamoto University Kumamoto Japan
Takeshi Motohara Department of Obstetrics and Gynecology Faculty of Life Sciences Kumamoto University Kumamoto Japan
ISBN 978-981-10-7940-5 ISBN 978-981-10-7941-2 (eBook) https://doi.org/10.1007/978-981-10-7941-2 Library of Congress Control Number: 2018940504 © Springer Nature Singapore Pte Ltd 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. part of Springer Nature The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Preface
The ovaries are not only a part of the reproductive system, which contains ova, but also a part of endocrine system, which secretes sex steroid hormones such as estrogen and progesterone. In 1651, an English physician William Harvey postulated “ex ovo omnia—all that is alive comes from the egg” in his book Exercitationes de Generatione Animalium. His insightful words, written almost four centuries ago, express the importance of the information stored in the ova and its mechanism in the development of a living being. This comprehensive book aims to provide extremely valuable reviews on the principles of the scientific biology of the ovary. Arranged thematically in sections, each chapter covers different but interrelated topics spanning across basic and clinical research. In this book, we present molecular mechanisms underlying ovarian development, e
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