Chemical Constituents and Pharmacological Effects of Genus Patrinia : a Review

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NATURAL PRODUCTS: FROM CHEMISTRY TO PHARMACOLOGY (C HO, SECTION EDITOR)

Chemical Constituents and Pharmacological Effects of Genus Patrinia: a Review Lijun Meng 1 & Sitan Chen 1 & Li Zhou 1 & Zhenhua Liu 1,2,3 & Shiming Li 1 & Wenyi Kang 1,2,3 Accepted: 8 September 2020 # Springer Nature Switzerland AG 2020

Abstract Purpose of Review To provide references for further research and for the application of the genus Patrinia, recent studies concerning the phytochemistry and pharmacology of the genus Patrinia were summarized. Recent Findings There are about 20 species of Patrinia genus around the world which is mainly distributed throughout East Asia and North America, and about 10 species, 3 subspecies, and 2 variant species in China which have been used as traditional Chinese medicine in controlling fever and inflammation along with detoxication, mobilization of blood circulation, and treatment for stasis, among others. The tender leaves of some species could be used for food. The main chemical constituents are triterpenoids, iridoids, flavonoids, anthraquinone, coumarin, lignans, steroids organic acids, and alkaloids in Patrinia. Pharmacology researches showed that Patrinia possesses sedative, antibacterial, antivirus, anti-tumor activities, and protective effects of liver and gallbladder. It can be used in the treatment of neurasthenia, hepatitis, and pneumonia. Summary The plant resources of genus Patrinia are rich; at the same time, the genus has complex chemical constituents and abundant pharmacological activities. Keywords Genus Patrinia . Chemical constituents . Pharmacology . Triterpenoids

Introduction There are about 20 species of genus Patrinia all over the world which are mainly distributed in East Asia and North America. Therein, about 10 species, 3 subspecies, and 2 variant species are native to China. According to the Chinese traditional This article is part of the Topical Collection on Natural Products: From Chemistry to Pharmacology * Zhenhua Liu [email protected] * Shiming Li [email protected] * Wenyi Kang [email protected] 1

National R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng 475004, China

2

Functional Food Engineering Technology Research Center, Kaifeng 475004, Henan Province, China

3

Joint International Research Laboratory of Food & Medicine Resource Function, Henan University, Kaifeng 475004, Henan Province, China

pharmaceutical books, 9 species and 2 subspecies have been used as medicinal herbs in China [1], which are widely distributed in the entire country. The Patrinia species in China include Patrinia scabiosaefolia Fisch. ex Trevir.; Patrinia sibirica (Linn.) Juss.; Patrinia glabrifolia Yamamoto et Sasaki; Patrinia speciosa Hand. Mazz; Patrinia intermedia (Horn.) Roem. et Sehult; Patrinia rupestris (Pall.) Juss.; subsp. rupestris; subsp. scabra (Bunge) H. J. Wang; Patrinia heterophylla Bunge; subsp. heterophylla; subsp. angustifolia (Hemsl.) H. J. Wang; Patrinia villosa (Thunb.) Juss.; subsp. punctifolia H. J. Wang; Patrinia punctiflora