Collagenase in Dupuytren Disease

This book offers detailed guidance on the use of collagenase, or enzymatic fasciotomy, as a nonsurgical treatment for Dupuytren’s contracture and explains its role in relation to the other forms of treatment, including open fasciectomy, needle aponeurotom

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Collagenase in Dupuytren Disease

Giorgio Pajardi Marie A. Badalamente Lawrence C. Hurst Editors

Collagenase in Dupuytren Disease

Editors Giorgio Pajardi Hand Surgery & Rehabilitation Department-Ospedale San Giuseppe MultiMedica Group - Milan Italy

Marie A. Badalamente Stony Brook University Medical Center New York USA

Plastic & Reconstructive Surgery School Università degli Studi di Milano Milano Italy Lawrence C. Hurst Department of Orthopaedics Stony Brook University Medical Center New York USA

ISBN 978-3-319-65821-6    ISBN 978-3-319-65822-3 (eBook) https://doi.org/10.1007/978-3-319-65822-3 Library of Congress Control Number: 2018940079 © Springer International Publishing AG, part of Springer Nature 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by the registered company Springer International Publishing AG part of Springer Nature The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Dedicated to the memory of Elisa Geranio, Editor at Springer, who conceived the publication of this book together with Prof. Giorgio Pajardi

Preface

When in 2010 I had the honor of leading an Italian delegation of leading expert hand surgeons to meet Marie and Lawrence at Stony Brook University, I never thought that today I would be reading the final draft of the first book dedicated to the use of collagenase for the treatment of Dupuytren contracture. Over the years, Dupuytren conctracture has been discussed at many congresses, written about in numerous publications, and the most innovative surgical techniques have been described—all while we believed that nothing could be done to prevent its recurrence. This book represents a cultural revolution. Collagenase is a wonderful idea that will change the lives of millions of patients. I believe that in the future collagenas