Correlates of aortic compliance and brachial artery flow mediated vasodilatation in normal subjects
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BioMed Central
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Poster presentation
Correlates of aortic compliance and brachial artery flow mediated vasodilatation in normal subjects Visali Kodali*, Yi Wang, Danielle Janosevic, Edwin Estrada, Willaim Schapiro, Simcha Pollack and Nathaniel Reichek Address: St. Francis Hospital, Roslyn, NY, USA * Corresponding author
from 13th Annual SCMR Scientific Sessions Phoenix, AZ, USA. 21-24 January 2010 Published: 21 January 2010 Journal of Cardiovascular Magnetic Resonance 2010, 12(Suppl 1):P145
doi:10.1186/1532-429X-12-S1-P145
Abstracts of the 13th Annual SCMR Scientific Sessions - 2010
Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/files/pdf/1532-429X-11-S1-infoThis abstract is available from: http://jcmr-online.com/content/12/S1/P145 © 2010 Kodali et al; licensee BioMed Central Ltd.
Introduction Vascular endothelial dysfunction appears in early atherosclerosis and is associated with adverse cardiovascular outcomes, while decreased aortic compliance (AC) is associated with aging, systolic hypertension and left ventricular diastolic dysfunction. It is believed that diabetes, hypertension, hyperlipidemia and obesity contribute to endothelial dysfunction, often measured using brachial artery flow mediated vasodilation (F). However, the determinants of AC and its relationship to abnormal F are not well understood.
Purpose We developed techniques to non-invasively quantify both AC and F in a single MR study and used this approach to examine their concordance and correlates in normal and hyperlipidemic subjects.
Methods Fifty one volunteers (26 females, 24 hyperlipidemics (11(46%) treated), age: 48.0 ± 4.3 yrs, body mass index (BMI)
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