Development of zinc-loaded nanoparticle hydrogel made from sugarcane bagasse for special medical application
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ORIGINAL ARTICLE
Development of zinc‑loaded nanoparticle hydrogel made from sugarcane bagasse for special medical application Harish Kumar1 · Avneesh Kumar Gehlaut1 · Ankur Gaur1 · Jin‑Won Park2 · Sanjeev Maken3 Received: 25 September 2019 / Accepted: 10 May 2020 © Springer Japan KK, part of Springer Nature 2020
Abstract This research is focused on the development of ZnO-NPs hydrogels through in situ method. The powerful absorption peak within the order of 320 nm confirms the presence of the zinc oxide nanoparticles arrangement because of the surface Plasmon resonance (SPR). ZnO-NPs characterization was performed by SEM, TEM, PSA, EDX, and FTIR. Additionally, the behaviour of prepared nanocomposite hydrogels swelling was examined at different pH and salt solutions. Furthermore, the antibacterial activity of ZnO-NPs hydrogels against Escherichia coli (ATCC 433) and Bacillus subtilis (ATCC 1688) was measured by the use of agar disk plate diffusion process. ZnO-NPs hydrogels extracted from lab-made CMC showed a greater antibacterial action through Gram-positive bacteria (B. subtilis) and Gram-negative bacteria (E. coli) relative to synthetic CMC acquired from the market. The hydrogels developed by ZnO-NPs can be utilized in biomedical applications efficiently.
* Ankur Gaur ‑[email protected] 1
Department of Chemical Engineering, Motilal Nehru National Institute of Technology, Allahabad 211004, Uttar Pradesh, India
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Department of Chemical and Biomolecular Engineering, Yonsei University, 262, Seoul 120‑749, Republic of Korea
3
Deen Bandhu Chotu Ram State University of Science and Technology, Murthal, India
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Vol.:(0123456789)
Journal of Material Cycles and Waste Management
Graphic abstract
Keywords Carboxymethyl cellulose (CMC) · Zinc oxide nanoparticles (ZnO-NPs) · Hydrogel · pH-sensitive · Antibacterial activity
Introduction Hydrogels are hydrophilic, linear, or branched polymers that are cross linked in three dimensions. They are competent in absorbing big amounts of water, salt, and physiological alternatives in comparison to common absorbent materials [1]. Due to their exceptional potential in a large range of applications, hydrogels have received tremendous attention over the past 50 years. High water content also gives them a degree of versatility just like natural tissue [2]. Chemical gels and physical gels can be categorized as hydrogels. Due to covalent bonding, chemical hydrogels are cross-linked. Although physical hydrogels are kept together by molecular secondary force of attractions, i.e., hydrogen bonding, hydrophobic forces, physical gels, however, consist of some in-homogeneities such as identifying molecular entanglements, cluster formation in ionically related fields, and the existence of free chain ends that initiate transient network failures [3]. Smart gels are synthesized for environmental conditions, such as
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pH, temperature, light, and electrical fields to maximize the ability of these hydrogels, and composed of polymer structure functional groups resulting fr
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