Dietary Omega-3 Polyunsaturated Fatty Acids and Cancer

Dietary Omega-3 Polyunsaturated Fatty Acids and Cancer provides all the latest information on the possible benefits of omega-3 polyunsaturated fatty acids (PUFAs) against a wide series of cancers. Several influential scientists in this field have contribu

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Series Editor Adriana Albini

For further volumes: http://www.springer.com/series/8049

Gabriella Calviello · Simona Serini Editors

Dietary Omega-3 Polyunsaturated Fatty Acids and Cancer

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Editors Prof. Gabriella Calviello Universit`a Cattolica Sacro Cuore - Roma Istituto di Patologia Generale Largo F. Vito, 1 00168 Roma Italy [email protected]

Dr. Simona Serini Universit`a Cattolica Sacro Cuore - Roma Istituto di Patologia Generale Largo F. Vito, 1 00168 Roma Italy [email protected]

ISBN 978-90-481-3578-3 e-ISBN 978-90-481-3579-0 DOI 10.1007/978-90-481-3579-0 Springer Dordrecht Heidelberg London New York Library of Congress Control Number: 2009942718 © Springer Science+Business Media B.V. 2010 No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Contents

Part I Possible Mechanisms 1 Possible Mechanisms of ω-3 PUFA Anti-tumour Action . . . . . . . Michael B. Sawyer and Catherine J. Field

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Part II ω-3 PUFAs and Colon Cancer 2 ω-3 PUFAs and Colon Cancer: Epidemiological Studies . . . . . . Yasumi Kimura

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3 ω-3 PUFAs and Colon Cancer: Experimental Studies and Human Interventional Trials . . . . . . . . . . . . . . . . . . . . . Simona Serini, Elisabetta Piccioni, and Gabriella Calviello

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Part III ω-3 PUFAs and Hormone-Related Cancers (Breast and Prostate) 4 ω-3 PUFAs and Breast Cancer: Epidemiological Studies . . . . . . Paul D. Terry and Pamela J. Mink

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5 ω-3 PUFAs and Prostate Cancer: Epidemiological Studies . . . . . Pierre Astorg

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6 ω-3 PUFAs: Interventional Trials for the Prevention and Treatment of Breast and Prostate Cancer . . . . . . . . . . . . . . Isabelle M. Berquin, Iris J. Edwards, Joseph T. O’Flaherty, and Yong Q. Chen

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7 ω-3 PUFAs, Breast and Prostate Cancer: Experimental Studies . . Iris J. Edwards, Isabelle M. Berquin, Yong Q. Chen, and Joseph T. O’Flaherty

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Part IV ω-3 PUFAs and Other Cancers 8 ω-3 PUFAs and Other Cancers . . . . . . . . . . . . . . . . . . . . Kyu Lim and Tong Wu

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Contents

9 The Influence of ω-3 PUFAs on Chemo- or Radiation Therapy for Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . W. Elaine Hardman

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ω-3 PUFAs and Cachexia . . . . . . . . . . . . . . . . . . . . . . . Michael J. Tisdale

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Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Contributors

Pierre Astorg Unité Nutrition et Régulation Lipidique des Fonctions Cérébrales (NuReLiCe), INRA, 78352 Jouy-en-Josas, France, [email protected] Isabelle M. Berquin Departments of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School