Disorders of Thrombosis and Hemostasis in Pregnancy A Guide to Manag

This comprehensive guide to disorders of thrombosis and hemostasis in pregnancy is an invaluable resource for those caring for women during pregnancy and fertility treatment, and for the neonate. It highlights the latest developments and controversial iss

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Disorders of Thrombosis and Hemostasis in Pregnancy

Hannah Cohen • Patrick O'Brien Editors

Disorders of Thrombosis and Hemostasis in Pregnancy A Guide to Management Second Edition

Editors Hannah Cohen Department of Haematology University College London Hospitals NHS Foundation Trust London UK

Patrick O'Brien Institute for Women’s Health University College London Hospitals NHS Foundation Trust London UK

ISBN 978-3-319-15119-9 ISBN 978-3-319-15120-5 DOI 10.1007/978-3-319-15120-5

(eBook)

Library of Congress Control Number: 2015936083

Springer Cham Heidelberg New York Dordrecht London © Springer-Verlag London 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface to the Second Edition

The first edition of this book quickly established itself as an invaluable resource for those caring for women during pregnancy and fertility treatment. This second edition expands its scope, including new chapters on anticoagulants and antiplatelet agents, cerebrovascular disease, pre-eclampsia, obstetric haemorrhage, thrombotic microangiopathies, paroxysmal nocturnal haemoglobinuria and analgesia and anaesthesia in women with haemostatic or thrombotic disorders in pregnancy. It also updates the previous content with the most recent research evidence. The book provides a contemporary and comprehensive guide to the management of haematological disorders in pregnancy. It covers a wide range of important clinical disorders that are associated with a potentially significant risk of morbidity and mortality in both the mother and the baby. The focus in each chapter is on authoritative, practical clinical advice, in the context of the available scientific evidence, on the management of women with both common and rare disorders of thrombosis and haemostasis in pregnancy. Included also are disorders where the management of thrombotic aspects are highly relevant, such as cardiac disorders, haem