EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging
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GUIDELINES
EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging Roberto Sciagrà 1 & Mark Lubberink 2,3 & Fabien Hyafil 4,5 & Antti Saraste 6,7 & Riemer H. J. A. Slart 8,9 & Denis Agostini 10 & Carmela Nappi 11 & Panagiotis Georgoulias 12 & Jan Bucerius 13 & Christoph Rischpler 14 & Hein J. Verberne 15 & Cardiovascular Committee of the European Association of Nuclear Medicine (EANM) Received: 18 August 2020 / Accepted: 17 September 2020 # The Author(s) 2020
Abstract The use of cardiac PET, and in particular of quantitative myocardial perfusion PET, has been growing during the last years, because scanners are becoming widely available and because several studies have convincingly demonstrated the advantages of this imaging approach. Therefore, there is a need of determining the procedural modalities for performing high-quality studies and obtaining from this demanding technique the most in terms of both measurement reliability and clinical data. Although the field is rapidly evolving, with progresses in hardware and software, and the near perspective of new tracers, the EANM Cardiovascular Committee found it reasonable and useful to expose in an updated text the state of the art of quantitative myocardial perfusion PET, in order to establish an effective use of this modality and to help implementing it on a wider basis. Together with the many steps necessary for the correct execution of quantitative measurements, the importance of a multiparametric approach and of a comprehensive and clinically useful report have been stressed. Keywords PET . Myocardial blood flow . Myocardial flow reserve . Quantitative imaging
This article is part of the Topical Collection on Cardiology These procedural guidelines are dedicated in memory of Prof. Eugenio Inglese, founding father of the Italian Group of Nuclear Cardiology and victim of COVID-19. * Roberto Sciagrà [email protected] 1
Nuclear Medicine Unit, Department of Experimental and Clinical Biomedical Sciences “Mario Serio”, University of Florence, Largo Brambilla 3, 50134 Florence, Italy
8
Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands
9
Faculty of Science and Technology Biomedical, Photonic Imaging, University of Twente, Enschede, The Netherlands
10
Department of Nuclear Medicine, CHU Cote de Nacre, Normandy University, EA 4650, Caen, France
11
Department of Advanced Biomedical Sciences, University Federico II, Naples, Italy
12
Department of Nuclear Medicine, Faculty of Medicine, University of Thessaly, University Hospital of Larissa, Larissa, Greece
2
Radiology & Molecular Imaging, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
3
Medical Physics, Uppsala University Hospital, Uppsala, Sweden
4
Department of Nuclear Medicine, DMU IMAGINA, APHP, Hôpital Européen Georges-Pompidou, University of Paris, Paris, France
13
Department of Nuclear Medicine, University Medicine Göttingen, Georg-August University Göttingen, Göttingen, Germany
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