Effect on intestinal microbiota, bioaccumulation, and oxidative stress of Carassius auratus gibelio under waterborne cad
- PDF / 1,937,476 Bytes
- 11 Pages / 547.087 x 737.008 pts Page_size
- 101 Downloads / 176 Views
Effect on intestinal microbiota, bioaccumulation, and oxidative stress of Carassius auratus gibelio under waterborne cadmium exposure Nan Wang & Zhengyao Guo & Yilin Zhang & Peijun Zhang & Jia Liu & Yi Cheng & Lei Zhang & Yuehong Li
Received: 8 February 2020 / Accepted: 28 August 2020 # Springer Nature B.V. 2020
Abstract Cadmium (Cd) is a hazardous pollutant known to exert various toxic effects and other sublethal effects on aquatic organisms, and induce a variety of adverse effects on human health, and can be commonly found in environment. The aim of this study was to explore the effects of waterborne Cd exposure on the intestinal microbiota, and Cd accumulation and oxidative response in Carassius auratus gibelio (C. gibelio). The fish were exposed to waterborne Cd at 0, 1, 2, and 4 mg/L for 30 days. Waterborne Cd exposure resulted marked alterations in the composition of microbiota. At the genus level, Bacteroides, Aeromonas, Akkermansia, Acinetobacter , Chryseobacterium, Shinella, Cetobacterium and Bacillus were significantly changed in Cd groups. The results obtained indicate that Cd exposure significantly increased the bioaccumulation level of Cd and profoundly affected antioxidant enzyme including superoxide dismutase (SOD), catalase (CAT), Nan Wang and Zhengyao Guo contributed equally to this work. N. Wang : Z. Guo : Y. Zhang : J. Liu : Y. Cheng : L. Zhang : Y. Li College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China N. Wang : Z. Guo : Y. Zhang : J. Liu : Y. Cheng : L. Zhang : Y. Li (*) Ministry of education laboratory of animal production and quality security, Jilin Agricultural University, Changchun 130118, China e-mail: [email protected] P. Zhang Health Monitoring and Inspection Center of Jilin Province, Changchun 130062, China
glutathione (GSH), total antioxidant (T-AOC), malonaldehyde (MDA), and glutathione-S-transferase (GST). The present findings may provide a new framework for the role of gut microbiota in the response to environmental chemical contamination and in the pathogenesis of body disorders. Keywords Intestinal microbiota . Cadmium . Accumulation . Antioxidant responses
Introduction Due to a wide range of industrial applications, from metal electroplating and batteries and solders used to prevent corrosion to acidic mine drainage (AMD) discharged from metal sulfide tailing (including waste rock), cadmium (Cd) has become an important pollutant with high toxicity and water solubility (Kraemer et al. 2005; Liu et al. 2014). As a biological non-essential element, Cd is recognized to be one of the most harmful heavy metal pollutants to the health of humans and other organisms, especially aquatic animals pose a serious threat, because it is not only readily assimilated and bioaccumulated at least in fish and in mammals, but it is highly toxic with 10 to 30 years of long biological half-time (Adeyeye et al. 1996; Danyang et al. 2018; Liu et al. 2014). Thus, the adverse effects of Cd on aquatic biota have aroused widely public concerns in recent years. G
Data Loading...
