Future Immunotherapy Challenges and Perspectives
The field of immunotherapy has progressed rapidly, expanding from the use of monoclonal antibodies and interferons, to more innovative approaches now being tested in laboratories and in the clinic. Several challenges still exist in the field, including ad
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notherapy – A Novel Facet of Modern Therapeutics
Immunotherapy – A Novel Facet of Modern Therapeutics
Sujata P. Sawarkar • Vandana S. Nikam • Shariq Syed Editors
Immunotherapy – A Novel Facet of Modern Therapeutics
Editors Sujata P. Sawarkar Department of Pharmaceutics SVKM’s Dr. Bhanuben Nanavati College of Pharmacy Mumbai, Maharashtra, India
Vandana S. Nikam Department of Pharmacology, STES’s Smt. Kashibai Navale College of Pharmacy S. P. Pune University Pune, Maharashtra, India
Shariq Syed School of Pharmacy Anjuman-I-Islam’s, Kalsekar Technical Campus Mumbai, Maharashtra, India
ISBN 978-981-15-9037-5 ISBN 978-981-15-9038-2 https://doi.org/10.1007/978-981-15-9038-2
(eBook)
# Springer Nature Singapore Pte Ltd. 2021 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Contents
1
Immunotherapy: A Concept . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Vritika Kulwal and Sujata Sawarkar
2
Immunotherapy in Cancer: Immune Checkpoint Inhibitors; Changing Oncology Treatment Paradigm . . . . . . . . . . . . . . . . . . . . Shariq Syed
1
21
3
Vaccines as Immunotherapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Pratik Ogale, Vandana S. Nikam, Manish Gautam, Sunil Gairola, and S. S. Jadhav
31
4
Immunotherapy for Autoimmune Diseases . . . . . . . . . . . . . . . . . . . Aniket Mali, Apurva Sawant, Anagha Mahadik, and Sujit Nair
63
5
Immunotherapy in Neurodegenerative Disorders . . . . . . . . . . . . . . 117 Dipanjali Kamthe, Netra Gosavi, and Vandana S. Nikam
6
Companion Diagnostics and Clinical Biomarkers for Immunotherapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137 Vandana S. Nikam
7
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