Gene Therapy for Cartilage and Bone Tissue Engineering
"Gene Therapy for Cartilage and Bone Tissue Engineering" outlines the tissue engineering and possible applications of gene therapy in the field of biomedical engineering as well as basic principles of gene therapy, vectors and gene delivery, specifically
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Yu-Chen Hu
Gene Therapy for Cartilage and Bone Tissue Engineering
123
SpringerBriefs in Bioengineering
For further volumes: http://www.springer.com/series/10280
Yu-Chen Hu
Gene Therapy for Cartilage and Bone Tissue Engineering
Yu-Chen Hu Department of Chemical Engineering National Tsing Hua University Taiwan, Republic of China
ISSN 2193-097X ISSN 2193-0988 (electronic) ISBN 978-3-642-53922-0 ISBN 978-3-642-53923-7 (eBook) DOI 10.1007/978-3-642-53923-7 Springer Heidelberg New York Dordrecht London Library of Congress Control Number: 2013958452 © The Author(s) 2014 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
Tissue engineering and gene therapy are both perceived important milestones of scientific achievements over the past two decades and both disciplines have converged for over 10 years. The past decade has witnessed rapid progresses in the gene delivery-based tissue engineering, especially for the repair of cartilage and bone defects. However, to date there still exist roadblocks to the translation of scientific findings in the laboratory to the clinical setting, because of the concerns regarding the use of gene therapy vectors for the treatment of non-lethal diseases/ disorders such as bone/cartilage defects. This book briefly summaries th
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