Highly Sensitive Polarimetric Sensor Based on Fano Resonance for DNA Hybridization Detection
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Highly Sensitive Polarimetric Sensor Based on Fano Resonance for DNA Hybridization Detection Xiang Zhao 1 & Tianye Huang 1 & Shuwen Zeng 2 & Chaolong Song 1 & Zhuo Cheng 1 & Xu Wu 1 & Pan Huang 1 & Jianxing Pan 1 & Yiheng Wu 1 & Perry Ping Shum 3 Received: 11 June 2019 / Accepted: 1 November 2019 # Springer Science+Business Media, LLC, part of Springer Nature 2019
Abstract Surface plasmon resonance (SPR) sensor based on reflectivity measurement has been widely studied for its convenient detection, high sensitivity, and real-time functions. However, the resonance curves of SPR reflectivity spectrum are broad that lead to a low detection limit (DL) and low detection resolution. In this work, Fano resonance (FR), which has an asymmetrical sharp and narrow resonance peak, is demonstrated here to improve the DL and resolution of the plasmonic sensor. More importantly, a three-point method is employed here to analyzed and extract the polarization information of the reflected light by replacing the conventional intensity interrogation method. The sharp signal change of the Fano resonance realized by the designed configuration together with the three-point method led to a significantly enhancement on the DL and the resolution of the FR-based sensor up to one order of magnitude comparing to conventional scheme commonly used with the commercial products. Thus, the proposed sensor is of great potential for biochemical sensing such as DNA detection in terms of measuring the refractive index change at the sensing interface. Keywords Fano resonance . Three-point method . Detection limit . Biochemical sensing
Introduction Surface plasmon resonance (SPR) is an optical phenomenon that occurs between two materials with negative and positive real parts of dielectric constants [1], respectively. When the parallel wave vector of incident light is matched with the propagation constant of the surface plasmon, free electrons on the metal surface can resonant with the incident photons and absorb light energy, thus causing a sharp attenuation of reflected light [2]. Due to the advantages of convenient detection, high sensitivity, and real-time functions, SPR sensors are widely applied to chemical and biomolecular detection [3–5]. However, the performance of the conventional SPR sensors is * Tianye Huang [email protected] * Zhuo Cheng [email protected] 1
School of Mechanical Engineering and Electronic Information, China University of Geosciences (Wuhan), Wuhan 430074, China
2
XLIM Research Institute, UMR 7252 CNRS/University of Limoges, 123, Avenue Albert Thomas, 87060 Limoges Cedex, France
3
Center of Fiber Technology, Electrical and Electronics Engineering, Nanyang Technological University, Singapore, Singapore
restricted by its broad resonance curve which corresponds to a low resolution or detection limit (DL) of the sensors. Therefore, to obtain a sharper resonance curve has become a research hotspot. For this purpose, different approaches including longrange surface plasmon resonance (LRSPR) [6], waveguidecoupled SPRs [7],
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