Infliximab
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Infliximab Infusion reaction: case report A 45-year-old man developed an infusion reaction while receiving infliximab [Remicade]. The man had been diagnosed with Crohn’s disease, and had a history of multiple ileostomies with multiple complications including peristomal pyodermal gangrenosum (PG). He started receiving infliximab [dosage and route not stated] but experienced an infusion reaction [duration of treatment to reaction onset and outcome not stated] and was switched to adalimumab. He received mild benefit although he continued to experience severe PG, requiring corticosteroids. He later received methotrexate, which worsened his symptoms significantly [details not stated]. Author comment: "The patient initially was treated with infliximab (Remicade), but experienced an infusion reaction. " Yoo L, et al. A case report of a patient with Crohn’s disease complicated by pyoderma gangrenosum treated with intravenous immunoglobulin. American Journal of Gastroenterology 108: S421 abstr. 1419, Oct 2013. Available from: 803096299 URL: http://dx.doi.org/10.1038/ajg.2013.267 - USA
0114-9954/13/1481-0001/$14.95 Adis © 2013 Springer International Publishing AG. All rights reserved
Reactions 7 Dec 2013 No. 1481
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