Infliximab

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Infliximab Lymphomatoid papulosis: case report A 21-year-old man, who was receiving IV infliximab [Remicade] 5 mg/kg every 12 weeks and azathioprine for ileocolic Crohn’s disease, developed progressive abdominal pain, anorexia, weight loss of –10 pounds and scattered violaceous papular nodules on his extremities and buttocks [duration of treatment before reaction onset not stated]. He received prednisone and his pain and anorexia subsequently improved, but his rash persisted; rash biopsies were consistent with lymphomatoid papulosis. Infliximab therapy was withdrawn, and the rash improved. He remained clinically well with continued azathioprine treatment. Outlaw W, et al. Development of lymphomatoid papulosis in a patient with Crohn’s disease treated with infliximab - a case report. American Journal of Gastroenterology 102 (Suppl. 2): 308 abstr. 522, Sep 2007 [abstract] 801083795 USA

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Reactions 27 Oct 2007 No. 1175