Long Acting Animal Health Drug Products Fundamentals and Application

This authoritative book is a comprehensive guide on the theories, applications, and challenges associated with the design and development of long acting veterinary formulations.  The volume acts as a reference to the animal health formulation scienti

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For further volumes: http://www.springer.com/series/8875

Michael J. Rathbone Arlene McDowell 

Editors

Long Acting Animal Health Drug Products Fundamentals and Applications

Editors Michael J. Rathbone Division of Pharmacy International Medical University Bukit Jalil, Kuala Lumpur, Malaysia

Arlene McDowell New Zealand’s National School of Pharmacy University of Otago Dunedin, New Zealand

ISSN 2192-6204 ISSN 2192-6212 (electronic) ISBN 978-1-4614-4438-1 ISBN 978-1-4614-4439-8 (eBook) DOI 10.1007/978-1-4614-4439-8 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2012948612 © Controlled Release Society 2013 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

This book is dedicated to my father George Frederick Rathbone who recently passed away… the man who gave me the wisest of my education

Preface

Long-acting veterinary formulations play a significant role in animal health, production, and reproduction within the animal health industry. Such technologies offer beneficial advantages to the veterinarian, farmer, and pet owner. These advantages have resulted in long-acting formulations growing in popularity in recent years. The pharmaceutical scientist is faced with many challenges when innovating new products in this demanding field of