Mass Spectrometry of Proteins Methods and Protocols
New insights into modern medicine and systems biology are enabled by innovative protocols and advanced technologies in mass spectrometry-based proteomics. This volume details new pipelines, workflows, and ways to process data that allow for new frontiers
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Caroline A. Evans · Phillip C. Wright Josselin Noirel Editors
Mass Spectrometry of Proteins Methods and Protocols
Methods
in
M o l e c u l a r B i o lo g y
Series Editor: John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Mass Spectrometry of Proteins Methods and Protocols
Edited by
Caroline A. Evans Department of Chemical and Biological Engineering, University of Sheffield, Sheffield, South Yorkshire, UK
Phillip C. Wright Faculty of Science, Agriculture & Engineering, Newcastle University, Newcastle upon Tyne, UK
Josselin Noirel Laboratoire GBCM (EA4627), Conservatoire National des Arts et Métiers HESAM Université, Paris, France
Editors Caroline A. Evans Department of Chemical and Biological Engineering University of Sheffield Sheffield, South Yorkshire, UK
Phillip C. Wright Faculty of Science, Agriculture & Engineering Newcastle University Newcastle upon Tyne, UK
Josselin Noirel Laboratoire GBCM (EA4627) Conservatoire National des Arts et Métiers HESAM Université Paris, France
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-9231-7 ISBN 978-1-4939-9232-4 (eBook) https://doi.org/10.1007/978-1-4939-9232-4 Library of Congress Control Number: 2019935881 © Springer Science+Business Media, LLC, part of Springer Nature 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Humana Press imprint is published by the registered company Springer Science+Business Media, LLC, part of Springer Nature. The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.
Preface Technological advancement in the life sciences has fostered a paradigm shift in data generation that is collectively known as “omics.” Systems biology, as it has come to be referred to, has become t
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