Molecular Diagnostics Part 1: Technical Backgrounds and Quality Aspe

The books Molecular Diagnostics Part 1 and 2 provide a comprehensive and practical overview of the state-of-the-art molecular biological diagnostic strategies that are being used in a wide variety of disciplines. The editors and experts in their respectiv

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Molecular Diagnostics Part 1: Technical Backgrounds and Quality Aspects

Molecular Diagnostics

E. van Pelt-Verkuil W. B. van Leeuwen R. te Witt •

Editors

Molecular Diagnostics Part 1: Technical Backgrounds and Quality Aspects

123

Editors E. van Pelt-Verkuil Leiden Centre for Applied Science, Faculty of Science & Technology University of Applied Sciences Leiden Leiden, The Netherlands

R. te Witt NMDL-LCPL Rijswijk, The Netherlands

W. B. van Leeuwen Leiden Centre for Applied Science, Faculty of Science & Technology University of Applied Sciences Leiden Leiden, The Netherlands

ISBN 978-981-13-1603-6 ISBN 978-981-13-1604-3 https://doi.org/10.1007/978-981-13-1604-3

(eBook)

Library of Congress Control Number: 2018948605 Molecular Diagnostics Part 1 is based at the Dutch book Moleculaire Diagnostiek (ISBN 9789077423950) that was published by Syntax Media in 2013. The text has been translated, and merely updated and extended at many points due to new insights and knowledge. © Springer Nature Singapore Pte Ltd. 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

Preface

In a very short historical time span of only 30 years, molecular diagnostic strategies have been efficiently embedded in a wide variety of both clinical, veterinary and agrobotanical disciplines. In 2001, E. van Pelt-Verkuil, M. F. van Berlo, A. van Belkum and H. G. M. Niesters once stood at the cradle of a first Dutch book on Molecular Diagnostics. In 2013, the second edition of Molecular Diagnostics was also published in the Dutch language: Moleculaire Diagnostiek. For this book copy, a new editorial team was formed, consisting of W. B. van Leeuwen and E. van Pelt-Verkuil. Immediately after publi