Neurodegenerative Diseases

The editor of this volume, having research interests in the field of ROS production and the damage to cellular systems, has identified a number of enzymes showing ·OH scavenging activities details of which are anticipated to be published in the near futur

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ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research JOHN D. LAMBRIS, University of Pennsylvania RODOLFO PAOLETTI, University of Milan

Recent Volumes in this Series Volume 716 MAST CELL BIOLOGY: CONTEMPORARY AND EMERGING TOPICS         Volume 717 KAINATE RECEPTORS: NOVEL SIGNALING INSIGHTS Antonio Rodriguez-Moreno and Talvinder S. Sihra Volume 718 BRAIN INSPIRED COGNITIVE SYSTEMS 2010 Ricardo Sanz, Jaime Gomez and Carlos Hernandez Volume 719 HOT TOPICS IN INFECTION AND IMMUNITY IN CHILDREN VIII Nigel Curtis Volume 720 HUMAN CELL TRANSFORMATION Johng S. Rhim and Richard Kremer Volume 721 SPHINGOLIPIDS AND METABOLIC DISEASE L. Ashley Cowart Volume 722 RNA INFRASTRUCTURE AND NETWORKS Lesley J. Collins Volume 723 RETINAL DEGENERATIVE DISEASES 

      !  "" and John D. Ash Volume 724 NEURODEGENERATIVE DISEASES Shamim I. Ahmad

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Neurodegenerative Diseases  Shamim I. Ahmad, BSc, MSc, PhD School of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom

Springer Science+Business Media, LLC Landes Bioscience

Springer Science+Business Media, LLC Landes Bioscience Copyright ©2012 Landes Bioscience and Springer Science+Business Media, LLC All rights reserved. *( k" ( #  " " "  " #'((  '  " '  &"#( " '  "(# >(" #(((  (# ('  >#"(# "; >#&#%#   k Printed in the USA. /( ' /q{# !@||/( '/ *} k*} k~[[~|/ http://www.springer.com % €# (#  Landes Bioscience, 1806 Rio Grande, Austin, Texas 78701, USA Phone: 512/ 637 6050; FAX: 512/ 637 6079 (++  " „( k & "!# {  (++  "+#  Neurodegenerative Diseases/""5 " {+/( ' /q{# Media, LLC dual imprint / Springer series: Advances in Experimental Medicine and Biology. ISBN: 978-1-4614-0652-5 …#  (# & #''( #' €#("& k  #  ""(  "(#"k >(