Neurodegenerative Diseases
The Role of Histone Deacetylases in Neurodegenerative Diseases and Small-Molecule Inhibitors as a Potential Therapeutic Approach.- Phosphodiesterase Inhibition to Target the Synaptic Dysfunction in Alzheimer’s Disease.- Glutamate and Neurodegenerative Dis
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Editorial Board: P. R. Bernstein · A. Buschauer · G. J. Georg · J. A. Lowe · H. U. Stilz
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Neurodegenerative Diseases Volume Editor: Celia Dominguez
With contributions by R. W. Bu¨rli K. R. Bales V. Beaumont S. Courtney A. Duplantier M. E. Gurney A. S. Kiselyov I. Mun˜oz-Sanjuan F. S. Menniti N. Plath E. Schaeffer A. Scheel N. Svenstrup E. Thomas
Editor Dr. Celia Dominguez CHDI Management Inc. Advisors to CHDI Foundation, Inc. Center Drive 6080 90045 Los Angeles California Suite 100 USA [email protected]
ISSN 1862-2461 e-ISSN 1862-247X ISBN 978-3-642-16757-7 e-ISBN 978-3-642-16758-4 DOI 10.1007/978-3-642-16758-4 Springer Heidelberg Dordrecht London New York # Springer-Verlag Berlin Heidelberg 2010 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Cover design: Ku¨nkelLopka GmbH, Heidelberg, Germany Typesetting and Production: SPi Publisher Services Springer is part of Springer ScienceþBusiness Media (www.springer.com)
Volume Editor Dr. Celia Dominguez CHDI Management Inc. Advisors to CHDI Foundation, Inc. Center Drive 6080 90045 Los Angeles California Suite 100 USA [email protected]
Editorial Board Dr. Peter R. Bernstein
John A. Lowe
AstraZeneca Pharmaceuticals 1800 Concord Pike Fairfax Research Center B313 PO Box 15437 Wilmington, DE 19850-5437 USA
[email protected]
Prof. Dr. Armin Buschauer
Dr. Hans Ulrich Stilz Aventis Pharma Deutschland GmbH Geb. G 838 65926 Frankfurt a.M. Germany
Institute of Pharmacy University of Regensburg Universita¨tsstr. 31 93053 Regensburg Germany
Prof. Dr. Gunda J. Georg University of Minnesota Department of Medical Chemistry 8-101A Weaver Densford Hall Minneapolis, MN 55455 USA
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