Novel Frontiers in the Production of Compounds for Biomedical Use
The present book entitled “Novel Frontiers in the Production of Compounds for Biomedical Uses” can perhaps be placed in its best perspective by the Shakespearean character in The Tempest who exclaimed" What’s past is prologue”. Indeed, this compilation of
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FOCUS ON BIOTECHNOLOGY Volume 1
Series Editors MARCEL HOFMAN Centre for Veterinary and Agrochemical Research Tervuren, Belgium
JOZEF ANNE Rega Institute, University of Leuven, Belgium
COLOPHON Focus on Biotechnology is an open-ended series of reference volumes produced for Kluwer Academic Publishers BV in co-operation with the Branche Belge de la Société de Chimie Industrielle a.s.b.l. The initiative has been taken in conjunction with the Ninth European Congress on Biotechnology. ECB9 has been supported by the Commission of the European Communities, the General Directorate for Technology, Research and Energy of the Wallonia Region, Belgium and J. Chabert, Minister for Economy of the Brussels Capital Region.
Novel Frontiers in the Production of Compounds for Biomedical Use, Volume 1
Edi ted by
ANNIE VAN BROEKHOVEN FRED SHAPIRO Innogenetics N.V., Ghent, Belgium and
JOZEF ANNÉ Catholic University of Leuven, Leuven, Belgium
KLUWER ACADEMIC PUBLISHERS NEW YORK / BOSTON / DORDRECHT / LONDON / MOSCOW
eBook ISBN: Print ISBN:
0-306-46885-9 0-792-36747-2
©2002 Kluwer Academic Publishers New York, Boston, Dordrecht, London, Moscow
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EDITORS PREFACE The present book entitled “Novel Frontiers in the Production of Compounds for Biomedical Uses” can perhaps be placed in its best perspective by the Shakespearean character in The Tempest who exclaimed" What’s past is prologue”. Indeed, this compilation of some of the outstanding presentations in the field of biomedicine made at the 9th European Congress on Biotechnology (Brussels, Belgium, July 11-15, 1999) not only reflects the achievements of the recent past, but provides a privileged glimpse of the biotechnology that is emerging in the first decade of the new Millennium. It is becoming increasingly apparent that biotechnology is offering biomedicine novel approaches and solutions to develop a sorely needed new generation of biopharmaceuticals. This is all the more necessary because in recent years, new diseases have emerged with extraordinary lethality in all corners of the globe, while age-related chronic illnesses have filled the gap wherever biomedicine has made successful inroads. The rise of antibiotic resistance also poses major threats to public health. Thus, as disease patterns evolve, the rational development of new drugs is becoming urgent, not only for the clinical outcome of patients, but also in optimising the allocation of scarce health care resources through the use of cost-effective productions methods. It is in response to all these challenges that biotechnology offers new strategies that go beyond the more traditional approaches. By the mid-1990’s, the number of recombinant products approved annual
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