Pathology of the Placenta A Practical Guide

This book provides a comprehensive resource on the pathology of the human singleton placenta. Agreed nomenclature, nosology, definitions and, where possible, thresholds for meaningful clinical corrections for lesions ideal for practical application in cli

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Pathology of the Placenta

T. Yee Khong  •  Eoghan E. Mooney Peter G. J. Nikkels  •  Terry K. Morgan Sanne J. Gordijn Editors

Pathology of the Placenta A Practical Guide

Editors T. Yee Khong Department of Anatomical Pathology Women’s and Children’s Hospital North Adelaide, South Australia Australia Peter G. J. Nikkels Department of Pathology University Medical Centre Utrecht Utrecht The Netherlands Sanne J. Gordijn Department of Obstetrics and Gynaecology University Medical Center Groningen University of Groningen Groningen The Netherlands

Eoghan E. Mooney Department of Pathology and Laboratory Medicine National Maternity Hospital Dublin Ireland Terry K. Morgan Department of Pathology Oregon Health and Science University Portland, OR USA

ISBN 978-3-319-97213-8    ISBN 978-3-319-97214-5 (eBook) https://doi.org/10.1007/978-3-319-97214-5 Library of Congress Control Number: 2018965177 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

The placenta is one of the most misunderstood and neglected tissues in anatomical pathology. It is a transient organ lasting only for the duration of a pregnancy and yet is of immense value to clinicians in understanding the success or otherwise of the pregnancy. It is also a unique organ in that it is a composite of two genomic contributions and cells derived from the placenta invade maternal tissue during pregnancy; thus, it is of interest to basic scientists studying immunology and cancer biology. This book describes the pathology of the human singleton third trimester placenta and builds on the initial effort of a group of pathologists, clinicians and scientists who met in Amsterdam in 2014. It aims to provi