Principles of Research Methodology A Guide for Clinical Investigator
Principles of Research Methodology: A Guide for Clinical Investigators is the definitive, comprehensive guide to understanding and performing clinical research. Designed for medical students, physicians, basic scientists involved in translational research
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Phyllis G. Supino • Jeffrey S. Borer Editors
Principles of Research Methodology A Guide for Clinical Investigators
Foreword by Stephen E. Epstein
Editors Phyllis G. Supino Professor of Medicine, College of Medicine Professor of Public Health, School of Public Heath Director of Clinical Epidemiology and Clinical Research Division of Cardiovascular Medicine State University of New York (SUNY) Downstate Medical Center Brooklyn, NY, USA Jeffrey S. Borer Professor and Chair, Department of Medicine Chief, Division of Cardiovascular Medicine Director of The Howard Gilman Institute for Heart Valve Disease Director of the Cardiovascular Translational Research Institute SUNY Downstate Medical Center Brooklyn, NY, USA
ISBN 978-1-4614-3359-0 e-ISBN 978-1-4614-3360-6 (eBook) DOI 10.1007/978-1-4614-3360-6 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2012937226 © Phyllis G. Supino and Jeffrey S. Borer 2012 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Foreword
This superb book on research philosophy and methodology that Drs. Phyllis Supino and Jeffrey Borer have written and edited came out of an experience common to most of us involved in training investigators beginning their research careers. How do you teach these investigators the mo
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