Proteases and Cancer Methods and Protocols
This volume explores the role of proteases in various catalytic classes and cellular processes associated with cancer. The chapters in this book cover topics such as encoding proteolytic enzymes, cleavage sites of proteases, functional catalytic domains o
- PDF / 10,410,933 Bytes
- 355 Pages / 504.63 x 737.01 pts Page_size
- 10 Downloads / 211 Views
Santiago Cal Alvaro J. Obaya Editors
Proteases and Cancer Methods and Protocols
Methods
in
Molecular Biology
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Proteases and Cancer Methods and Protocols
Edited by
Santiago Cal and Alvaro J. Obaya Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Asturias, Spain
Editors Santiago Cal Instituto Universitario de Oncología (IUOPA) Universidad de Oviedo Oviedo, Asturias, Spain
Alvaro J. Obaya Instituto Universitario de Oncología (IUOPA) Universidad de Oviedo Oviedo, Asturias, Spain
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-7594-5 ISBN 978-1-4939-7595-2 (eBook) https://doi.org/10.1007/978-1-4939-7595-2 Library of Congress Control Number: 2017963090 © Springer Science+Business Media, LLC 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Humana Press imprint is published by Springer Nature The registered company is Springer Science+Business Media, LLC The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.
Preface Proteases are widely involved in homeostatic processes, and hence they are also important players in different biological settings such as development, apoptosis, reproduction, host defense, or blood coagulation, among others. Consequently, alterations in the activity of these proteolytic enzymes are involved in a plethora of pathological diseases. In fact, proteases are crucial factors in the regulation and maintenance of all biological events regarding tissue wealth and organization, from keeping the correct cellular microenvironment to their involvement in important intracellular processes. As an example to which many
Data Loading...