Cancer Cytogenetics Methods and Protocols
Cytogenetic studies of malignancy have become an essential tool in the clinical management of cancer patients. Cancer Cytogenetics: Methods and Protocols presents eminently practical key c
- PDF / 8,433,217 Bytes
- 278 Pages / 504 x 720 pts Page_size
- 95 Downloads / 200 Views
in
Molecular Biology™
Series Editor John M. Walker School of Life Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
wwwwwwwwwwww
Cancer Cytogenetics Methods and Protocols Second Edition
Edited by
Lynda J. Campbell Victorian Cancer Cytogenetics Service, St. Vincent’s Hospital Melbourne, Fitzroy, VIC, Australia
Editor Lynda J. Campbell Victorian Cancer Cytogenetics Service St. Vincent’s Hospital Melbourne Fitzroy, VIC, Australia [email protected]
ISSN 1064-3745 e-ISSN 1940-6029 ISBN 978-1-61779-073-7 e-ISBN 978-1-61779-074-4 DOI 10.1007/978-1-61779-074-4 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011922375 © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Printed on acid-free paper Humana Press is part of Springer Science+Business Media (www.springer.com)
Preface This book comprises a series of chapters describing conventional cytogenetic analysis methods, fluorescence in situ hybridization and array methods. All of these techniques have been presented in the context of their use in the diagnosis and investigation of different varieties of cancer. The authors of the different chapters have provided both standard methods and also extensive notes to guide individuals who are new to these methods through the pitfalls that bedevil all such testing. The experience of the authors should enable all testing to be readily transferable. Inevitably, there are some areas of repetition as the methods for preparing chromosomes for analysis in the setting of myelodysplastic syndromes are similar to those methods used to analyse chronic myeloid leukaemia or acute myeloid leukaemia. However, every laboratory uses slight variations in their methods, and it is these differences that should prove useful to both novice and experienced cytogeneticists. Hopefully, readers will be able to either establish new techniques in their laboratories or will find the different variations of standard methods helpful in improving their results. The pace of change in scientific and medical research condemns most text books to being out of date by the time they are published. However, while some of the data presented here concerning the standard testing algorithms for different di
Data Loading...
