130 Contrast-enhanced whole-heart coronary MR angiography at 3.0 T: comparison to steady-state free precession technique
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Meeting abstract
130 Contrast-enhanced whole-heart coronary MR angiography at 3.0 T: comparison to steady-state free precession technique at 1.5 T Xin Liu*1, Xiaoming Bi2, Nondas Leloudas1, Renate Jerecic2, James Carr1 and Debiao Li1 Address: 1Northwestern University, Chicago, IL, USA and 2Siemens Medical Solutions, Chicago, IL, USA * Corresponding author
from 11th Annual SCMR Scientific Sessions Los Angeles, CA, USA. 1–3 February 2008 Published: 22 October 2008 Journal of Cardiovascular Magnetic Resonance 2008, 10(Suppl 1):A31
doi:10.1186/1532-429X-10-S1-A31
Abstracts of the 11th Annual SCMR Scientific Sessions - 2008
Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1532-429X-10-S1-info.pdfThis abstract is available from: http://jcmr-online.com/content/10/S1/A31 © 2008 Liu et al; licensee BioMed Central Ltd.
Introduction Contrast-enhanced whole-heart MRA using slow infusion of a high-relaxivity extravascular contrast agent has been shown to be a promising technique for imaging coronary arteries at 3.0 T (Bi X, Carr J, Li D. MRM 2007, 58: 1–7). Steady-state free precession (SSFP) is the most commonly used method for coronary MRA at 1.5 T. A direct comparison of the two techniques will be useful to demonstrate the advantages of coronary MRA at 3.0 T.
Purpose To compare contrast-enhanced whole-heart MRA at 3.0 T and non-contrast SSFP coronary MRA at 1.5 T in the same volunteers.
Methods Ten healthy volunteers (mean age 51 years) were recruited for this study and each subject underwent both 3.0 T and 1.5 T coronary MRA in random order. The interval of the two examinations was within two weeks. No beta-blocker or nitroglycerine was administrated to any subject. All studies were performed on two Siemens whole-body scanners (1.5 T: Avanto; 3.0 T: Tim Trio; Siemens Medical Solutions). Segmented 3D SSFP and 3D contrastenhanced FLASH techniques were employed at 1.5 T and 3.0 T, respectively. All data were collected with real-time motion adaptive navigator respiratory gating, ECG triggering, and fat saturation. T2 preparation (40 msec) was applied at 1.5 T to improve the blood-myocardial con-
trast. At 3.0 T, signal-to-noise ratio (SNR) and contrast-tonoise ratio (CNR) were optimized by applying a nonselective inversion pulse (TI = 200 msec), accompanied by slowly injecting (0.3 ml/sec) of 0.2 mmol/kg body weight of MultiHance (Bracco Imaging SpA, Milan, Italy). The same number of partitions (120–144), spatial resolution (1.4 × 1.4 × 0.9 mm3), GRAPPA (factor of 2), and 12 channel matrix coil were used in 3.0 T and 1.5 T coronary MRA. SNR and CNR of coronary arteries were measured from original images by a radiologist blinded to all study and volunteer information. The image quality and coverage of coronary anatomy were evaluated independently by two observers using original images of the coronary MRA. The image quality was graded as 1, poor; 2, fair; 3, good; and 4, excellent. The coverage o
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