2009 EuroMeeting Student Poster Abstracts

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2009 EuroMeeting Student Poster Abstracts Student Poster ScssionAbstracts thbathave tkc prcss date of this issue. Tke studmt at the DIA 21st A n d Eun, Meeting, M d 23-25. lntemationaies congrcpS Cen-

A single blind, placebo controlled clinical trial to evaluate the short term effect of Bacopa mooneiri formulation in enhancing the psychomotor performance of normal healthy volunteers using mindomatics software Ankur Kripa Shankar Pandey Bhandup. Mumbai, India Objective To assess short term effect of a classical Ayurvedic formulation of Bacopa mooneiri in calorified butter on psychomotor performance in healthy volunteers using a standardized and validated computerised tests and to compare the results with vehicle control, chlorpheniramine maleate (CPM) and coffee. Method Institutional Ethics Committee approval taken, 2 0 normal healthy volunteers screened, recruited and informed consent taken. Volunteers trained, tests performed-basal with CPM (75 mg) and coffee (150 mg powder). Study drug and vehicle control administered (2 tsp once daily for 1 month) and tests performed. Results Formulation betters motor performance, recent memory, attention, integration, co-ordination, sensory-motor performance significantly compared to vehicle and CPM, while effects were akin to coffee. It showed improvement in central integration and visual motor co-ordination, though not significant by stats. Conclusion This formulation of 4 potential drugs in calorified butter has a potential to improve the psychomotor performance which needs to be confirmed further through trials in cognitive disorders. Our results document for the first time that an Ayurvedic formulation improves psychomotor performance.

tnim, M i n , Getmany. The poster rcvicw committeewill sekct the winningpostem on M q March 24, and the winh g olrthors will receive a euroMecting Student Poster prize.

Method Literature research using MEDLINE, cross-reference of published data and review of World Health Organization-Pharmacovigilance transcripts, surgery and dentistry transcripts pertaining to pharmacovigilance. Results Pharmacovigilance system is in its infancy in surgery and dentistry. The target health care professionals are least likely to report an adverse drug reaction. Reasons and recommendations are put forward. Three tier approach and six sigma methodology will be presented to overcome the issue. Conc1usion With growing awareness of pharmacovigilance in various fields of medicine, surgery/dentistry can no longer remain an exception. In the transition from medical school to surgery/dental clinic a subtle shift must occur from emphasizing pharmacokinetics to appreciating pharmacodynamics.

Genetic and environmental factors determining clinical outcomes associated with warfarin therapy: a prospective study Andrea Jorgensen University of Liverpool, United Kingdom Objective To evaluate the impact of environmental and genetic factors on warfarin response in patients being initiated on warfarin, a prospective study of 1,000 patients was undertaken. Method Patients