Cutaneous Neural Neoplasms A Practical Guide
As a result to the recent significant developments, both in the field of cutaneous pathology and clinical dermatology, many cutaneous neural tumors are now being diagnosed by specialists like dermatopathologists, and treated by dermatologists or dermatolo
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Zsolt Argenyi • Chris H. Jokinen
Cutaneous Neural Neoplasms A Practical Guide
Zsolt Argenyi, M.D. Professor of Pathology and Dermatology Director of Dermatopathology Division 1959 NE Pacific St. 98195-6100 Seattle Washington USA [email protected]
Chris H. Jokinen, M.D. Essentia Health, Duluth Clinic Department of Pathology 407 East Third Street 55811 Duluth Minnesota USA [email protected]
ISBN 978-1-60327-581-1 e-ISBN 978-1-60327-582-8 DOI 10.1007/978-1-60327-582-8 Springer New York Dordrecht Heidelberg London © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Printed on acid-free paper Humana Press is part of Springer Science+Business Media (www.springer.com)
This work is dedicated to the memory of my father. —ZA This work is dedicated to Shawna for your support, patience and strength. —CHJ
Preface
Cutaneous neuropathology seems a small and esoteric field within the extensive domain of dermatopathology. Paradoxically, tumors of this category include some of the most vexing problems that dermatopathologists encounter in their daily practice. Since peripheral neural tumors are soft tissue tumors, they are studied and diagnosed by general pathologists or by soft tissue specialists. However, many neural tumors that occur in the skin or in superficial soft tissues are first seen by dermatologists or by dermatopathologists, who may not be familiar with the fine details of relevant neuropathology. Because of this division of diagnostic histopathology, cutaneous neuropathology became somewhat of a “no man’s land.” Present monograph intends to fill this gap in diagnostic dermatopathology. It is a practical guide with abundant illustrations of variants of common cutaneous neural neoplasms. Like any field of medicine, cutaneous neuropathology is ever evolving; therefore, changes in nomenclature and classification can be expected. For practical reasons we have used the current terminology and accepted classification with the understanding that the definition of some entities may change. Regardless of the most recent concepts of pathogenesis, every skin lesion should be classified for the ultimate purpose of diagnostic pathology, name
